Page last updated: 2024-09-28

4-[(4-phenyl-2-thiazolyl)amino]benzenesulfonamide

Cross-References

ID SourceID
PubMed CID768056
CHEMBL ID178489
CHEBI ID103884
SCHEMBL ID22680557

Synonyms (25)

Synonym
NCGC00262411-01
4-(4-phenyl-thiazol-2-ylamino)-benzenesulfonamide
OPREA1_625074
OPREA1_773463
EU-0011430
STK000436
4-[(4-phenyl-1,3-thiazol-2-yl)amino]benzenesulfonamide
66121-82-2
4-[(4-phenyl-2-thiazolyl)amino]-benzenesulfonamide
CHEMBL178489 ,
AKOS000565120
CHEBI:103884
4-(4-phenylthiazol-2-ylamino)benzenesulfonamide
bdbm50293571
CCG-20344
AB00101156-09
AB00101156-01
cambridge id 5930887
SR-01000492469-1
sr-01000492469
4-[(4-phenyl-2-thiazolyl)amino]benzenesulfonamide
Q27181076
DTXSID40354296
NCGC00262411-02
SCHEMBL22680557

Drug Classes (1)

ClassDescription
sulfonamideAn amide of a sulfonic acid RS(=O)2NR'2.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein Targets (2)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
ubiquitin carboxyl-terminal hydrolase 2 isoform aHomo sapiens (human)Potency21.67120.65619.452025.1189AID652173
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Inhibition Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
Fructose-1,6-bisphosphatase 1Sus scrofa (pig)IC50 (µMol)145.00001.10001.32501.6000AID419859
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (6)

Assay IDTitleYearJournalArticle
AID419859Inhibition of pig FBPase expressed in Escherichia coli EK1601 by spectrophotometry2009Bioorganic & medicinal chemistry, Jun-01, Volume: 17, Issue:11
A library of novel allosteric inhibitors against fructose 1,6-bisphosphatase.
AID244377Inhibition of COX-1 in human immunoassay2005Journal of medicinal chemistry, Feb-24, Volume: 48, Issue:4
Optimization and validation of a docking-scoring protocol; application to virtual screening for COX-2 inhibitors.
AID244378Inhibition of COX-2 in human immunoassay2005Journal of medicinal chemistry, Feb-24, Volume: 48, Issue:4
Optimization and validation of a docking-scoring protocol; application to virtual screening for COX-2 inhibitors.
AID1159537qHTS screening for TAG (triacylglycerol) accumulators in algae2017Plant physiology, Aug, Volume: 174, Issue:4
Identification and Metabolite Profiling of Chemical Activators of Lipid Accumulation in Green Algae.
AID1794808Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL).2014Journal of biomolecular screening, Jul, Volume: 19, Issue:6
A High-Throughput Assay to Identify Inhibitors of the Apicoplast DNA Polymerase from Plasmodium falciparum.
AID1794808Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL).
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's1 (20.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]